Reviscon in the Joint Cavity
- Masks the pain receptors by HA layer it forms.
- Helps the stimulation of new HA synthesis by the stimulation of synoviocytes and chondrocytes.
- Because of its filter function; while it is allowing the passage of cells that is needed by cartilage, synovium and synovial fluid; it prevents the infiltration of inflammatory cells.
- By its shock-absorbing effect, it smooths the force of sudden movement and preserves the joint
- Because of its barrier function, it prevents the destructive molecules such as proteases, pro-inflammatory cytokines and free oxygen radicals to reach cartilage and synovium
- Contributes the preservation and construction of joint cartilage and synovial membrane.
High Molecular Weight NaHA Line
Reviscon 20mg | Reviscon Plus 32mg | Reviscon Mono 48mg | |
Substance | Sodium Hyaluronate (NaHA) | Sodium Hyaluronate (NaHA) | Sodium Hyaluronate (NaHA) |
Concentration | 20 mg HA (1.0%) | 32 mg HA (1.6%) | 48 mg HA (2.0%) |
Volume | 2 ml | 2 ml | 2.4 ml |
Frequency | 3-5 injections with one week intervals | 1-3 injections with one week intervals | 1 injection only |
Origin | Bacterial Fermentation | Bacterial Fermentation | Bacterial Fermentation |
Moleculer Weight | 3.0 M Da | 3.0 M Da | 3.0 M Da |
Zero Shear Viscosity | 35,000 mPa.s | 250,000 mPa.s | 900,000 mPa.s |
Reviscon, Reviscon Plus and Reviscon Mono
- Reviscon, Reviscon Plus, and Reviscon Mono are intra-articular injections that contains hyaluronic acid solution.
- They are prefilled syringes for single use for intra-articular injection.
- Reviscon contains 1% hyaluronic acid (20 mg/2 ml).
- Reviscon Plus contains 1.6% hyaluronic acid (32 mg/2 ml).
- Reviscon Mono contains 2.0% hyaluronic acid (48 mg/2.4 ml).
Indication of Reviscon
It is used in the treatment of pain and loss of flexibility as a result of degenerative and traumatic changes in any synovial joint (flexible joints; such as knees, hips, shoulders, elbows, finger and toes).
It is indicated in the cases that had inadequate response to non-pharmacological conservative therapy and simple analgesics.Treatment can be applied to more than one joint at the same time. Therapy course may be repeated when needed.